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[汗液检测:技术要求综述]

[Sweat testing: review of technical requirements].

作者信息

Rota M, Nguyen-Khoa T, Marchand M, Feldmann D, Dumont J, Khalfon D, Vassault A, Borgard J-P

机构信息

Service de biochimie, CHI de Créteil.

出版信息

Ann Biol Clin (Paris). 2008 Mar-Apr;66(2):221-7. doi: 10.1684/abc.2008.0214.

Abstract

The sweat test, a quantitative measurement of chloride in sweat, remains a key laboratory test to support the diagnosis of cystic fibrosis. However, because of its delicate execution, sweat test result should be interpreted with biological, clinical and genetic arguments. The following guidelines which we propose, were established in order to harmonize the practices of the sweat test. They are elaborated in a consensual way by biologists from cystic fibrosis reference centers and/or from the working group "Sweat Testing" of the National College of Biochemistry Hospital praticiens, according to the current state of knowledge on the subject, the experiment of the biologists and the recommendations established in the United States and in the United Kingdom.

摘要

汗液测试,即对汗液中氯化物进行定量测量,仍然是支持囊性纤维化诊断的关键实验室检测。然而,由于其操作精细,汗液测试结果应结合生物学、临床和遗传学依据进行解读。我们提出的以下指南旨在统一汗液测试的操作规范。这些指南是由囊性纤维化参考中心的生物学家和/或国家生物化学医院从业者学院“汗液测试”工作组的生物学家,根据该主题的现有知识、生物学家的实验以及美国和英国制定的建议,以协商一致的方式制定的。

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