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胸椎后纵韧带骨化症(OPLL)前路减压治疗的临床结果

Clinical results of ossification of the posterior longitudinal ligament (OPLL) of the thoracic spine treated by anterior decompression.

作者信息

Min Jun-Hong, Jang Jee-Soo, Lee Sang-Ho

机构信息

Department of Neurosurgery, Gimpo Airport Wooridul Spine Hospital, Seoul, Korea.

出版信息

J Spinal Disord Tech. 2008 Apr;21(2):116-9. doi: 10.1097/BSD.0b013e318060091a.

Abstract

STUDY DESIGN

A retrospective study.

OBJECTIVE

To evaluate surgical outcomes and prognostic factors of thoracic ossification of the posterior longitudinal ligament (OPLL) treated by anterior decompression.

SUMMARY OF BACKGROUND DATA

The results of surgery for thoracic myelopathy caused by OPLL have been recognized as unfavorable. Anterior decompression is the logical treatment option for thoracic OPLL, but it is technically demanding and is associated with a high rate of complications.

METHODS

Nineteen patients who underwent anterior decompression were included in this study. Modified Japanese Orthopedic Association (JOA) scores and recovery rates were used to evaluate the outcomes. The relationship between the recovery rate and the following factors was investigated statistically: age, sex, duration of symptoms, preoperative JOA score, the degree of stenosis, the extent of decompression, the type of OPLL, the presence of signs of dural penetration, the presence of cerebrospinal fluid leakage, the presence of high signal intensity in the cord, and the presence of coexisting pathologies requiring surgical intervention.

RESULTS

The final outcome was excellent in 4 (21.1%) patients, good in 2 (10.5%), fair in 7 (36.8%), unchanged in 4 (21.1%), and worsened in 2 (10.5%). The only statistically significant factor affecting outcomes was the preoperative JOA score. The complications included 2 (10.5%) patients with neurologic deterioration and 6 (31.6%) patients with cerebrospinal fluid leakage.

CONCLUSIONS

We evaluated the outcomes and factors affecting the surgical outcomes of 19 patients with thoracic OPLL treated with anterior decompression. In this small series, we found that some patients undergoing anterior decompression for thoracic OPLL clinically improved, however, a significant percentage did not. Anterior decompression is technically demanding and is associated with a high rate of complications. When poor preoperative JOA scores and immediate postoperative neurologic deterioration are present, poor outcomes may be expected.

摘要

研究设计

一项回顾性研究。

目的

评估经前路减压治疗胸段后纵韧带骨化症(OPLL)的手术效果及预后因素。

背景资料总结

OPLL所致胸段脊髓病的手术效果一直被认为不佳。前路减压是治疗胸段OPLL的合理选择,但技术要求高且并发症发生率高。

方法

本研究纳入19例行前路减压的患者。采用改良日本骨科协会(JOA)评分和恢复率评估手术效果。对恢复率与以下因素的关系进行统计学研究:年龄、性别、症状持续时间、术前JOA评分、狭窄程度、减压范围、OPLL类型、硬脊膜穿透体征、脑脊液漏、脊髓内高信号强度以及是否存在需要手术干预的并存病变。

结果

最终结果为优的患者有4例(21.1%),良的有2例(10.5%),可的有7例(36.8%),不变的有4例(21.1%),恶化的有2例(10.5%)。影响手术效果的唯一具有统计学意义的因素是术前JOA评分。并发症包括2例(10.5%)神经功能恶化患者和6例(31.6%)脑脊液漏患者。

结论

我们评估了19例接受前路减压治疗的胸段OPLL患者的手术效果及影响手术效果的因素。在这个小样本系列研究中,我们发现一些接受胸段OPLL前路减压的患者临床症状有所改善,但仍有相当比例的患者没有改善。前路减压技术要求高且并发症发生率高。当术前JOA评分低且术后立即出现神经功能恶化时,可能预期手术效果不佳。

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