Park Bernard J
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Semin Thorac Cardiovasc Surg. 2007 Winter;19(4):374-9. doi: 10.1053/j.semtcvs.2007.10.003.
Improvements in the perioperative management of the patient undergoing pulmonary resections have reduced postoperative complication rates steadily in the last several decades. However, postresection respiratory failure, particularly lung injury with no discernible cause, remains a major cause of morbidity and mortality. Because the incidence of this entity is relatively low, the terminology, pathogenesis, and optimal management are poorly delineated in the literature. The purpose of this review is to describe the criteria used to define postresection lung injury, discuss the possible etiologic factors, and outline currently available treatment strategies.
在过去几十年中,肺切除患者围手术期管理的改善使术后并发症发生率稳步下降。然而,切除术后呼吸衰竭,尤其是无明显病因的肺损伤,仍然是发病和死亡的主要原因。由于这种情况的发生率相对较低,其术语、发病机制和最佳管理在文献中描述甚少。本综述的目的是描述用于定义切除术后肺损伤的标准,讨论可能的病因,并概述目前可用的治疗策略。