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一名产科患者发生的输血相关急性肺损伤(TRALI)。

Transfusion-related acute lung injury (TRALI) in an obstetric patient.

作者信息

Michala L, Madhavan B, Win N, De Lord C, Brown R

机构信息

Princess Royal University Hospital, Farnborough Common, Orpington, UK.

出版信息

Int J Obstet Anesth. 2008 Jan;17(1):66-9. doi: 10.1016/j.ijoa.2007.07.002.

Abstract

Transfusion-related lung injury (TRALI) is the leading cause of mortality following transfusion of blood products. Despite increasing awareness, the condition often remains unrecognised and therefore underreported. A 28-year-old with moderate preeclampsia had a post-partum haemorrhage following emergency caesarean section. Shortly after receiving three units of packed red cells she went into respiratory failure, which progressed to cardiac arrest. She was successfully resuscitated and made a slow but full recovery. Investigation through the National Blood Service confirmed the diagnosis of TRALI. TRALI is an increasingly common life-threatening complication of blood transfusion and should be included in the differential diagnosis of collapse in an obstetric patient who has recently received a blood product transfusion.

摘要

输血相关的肺损伤(TRALI)是输注血液制品后导致死亡的主要原因。尽管人们的认识不断提高,但这种情况往往仍未被识别,因此报告不足。一名28岁的中度子痫前期患者在急诊剖宫产术后发生产后出血。在输注三单位浓缩红细胞后不久,她出现呼吸衰竭,并进展为心脏骤停。她成功复苏,恢复缓慢但完全康复。通过国家血液服务机构进行的调查证实了TRALI的诊断。TRALI是一种越来越常见的危及生命的输血并发症,在近期接受过血液制品输血的产科患者发生虚脱的鉴别诊断中应予以考虑。

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