Boussemart T, Flurin V, Labay-Bruneau F, Bonardi J-M
Unité de réanimation pédiatrique, service de pédiatrie centre hospitalier du Mans, 194 avenue Rubillard, Le Mans cedex, France.
Arch Pediatr. 2008 Apr;15(4):416-8. doi: 10.1016/j.arcped.2008.01.020.
Heatstroke, which is a major disorder related to environmental hyperthermia, is a rare event in children. The risk is increased with predisposing medical conditions and specific medications. We report the case of a 10-year-old epileptic patient, who received topiramate. Topiramate causes hypohydrosis and hyperthermia. We suggest that topiramate treatment may be a risk factor for heatstroke.