Che Xu, Shan Yi, Zhou Zhi-Xiang, Zhao Dong-Bing, Bi Jian-Jun, Shao Yong-Fu, Zhao Ping
Department of Abdominal Surgical Oncology, Cancer Hospital (Institute), Chinese Academy of Medical Sciences, Beijing 100021, China.
Zhonghua Zhong Liu Za Zhi. 2007 Nov;29(11):864-6.
To summarize the surgical treatment experiece and to investigate the prognosis of the patients with ovarian metastasis from colorectal cancer.
The data of 67 patients with synchronous or asynchronous ovarian metastasis from colorectal cancer surgically treated between January 1989 and December 2005 were collected and analyzed retrospectively using Statistical Package for the Social Sciences (Release 11.5, SPSS, Inc). Prognostic factors were analyzed using chi2 test. Survival analysis was estimated by the Kaplan-Meier method and compared using the log-rank test. Multivariate analysis was carried out by Cox regression.
The overall 1-, 3- and 5-year survival of these 67 patients was 71.0%, 18.7% and 9.2%, respectively. Univariate analysis revealed that the metastasis was confined in the ovary or pelvis only, unilateral/double ovarian metastasis, and operation mode were all statistically significant prognostic factors (P <0.05). Cox regression analysis showed that the operation mode was the most important prognostic factor (OR = 3.531, P <0.001).
Surgical treatment is still the most effective mode in the treatment for the ovary metastasis from colorectal cancer.
总结结直肠癌卵巢转移患者的外科治疗经验并探讨其预后情况。
收集1989年1月至2005年12月期间接受手术治疗的67例结直肠癌同步或异时性卵巢转移患者的数据，采用社会科学统计软件包（版本11.5，SPSS公司）进行回顾性分析。使用卡方检验分析预后因素。采用Kaplan-Meier法估计生存分析，并使用对数秩检验进行比较。通过Cox回归进行多因素分析。
这67例患者的1年、3年和5年总生存率分别为71.0%、18.7%和9.2%。单因素分析显示，转移仅局限于卵巢或盆腔、单侧/双侧卵巢转移以及手术方式均为具有统计学意义的预后因素（P<0.05）。Cox回归分析表明，手术方式是最重要的预后因素（OR = 3.531，P<0.001）。
外科治疗仍是结直肠癌卵巢转移治疗中最有效的方式。
