Hillen Uwe
Department of Dermatology, Allergy and Venereology, University of Essen, Essen, Germany.
J Dtsch Dermatol Ges. 2008 Oct;6(10):857-9, 857-60. doi: 10.1111/j.1610-0387.2008.06663.x. Epub 2008 Apr 7.
A 57-year-old man presented with a persistent arcuate partly reticular erythema of the upper chest. Histopathological examination revealed an upper and mid-dermal perivascular and interstitial dermatitis with macrophages which had engulfed elastic fibers. Additionally a focal dermal elastolysis was observed. The characteristic clinicopathological constellation has hitherto been reported in only 3 cases, including our case. Presumably, the disease belongs to a spectrum of clinical manifestation of mid-dermal elastolysis. It is suggested to gather future cases under the provisional diagnosis ''reticular erythema with focal mid-dermal elastophagocytosis" (REMDE) to gain more insights into this rare disease.
一名57岁男性,上胸部出现持续性弓形部分网状红斑。组织病理学检查显示真皮上部和中部血管周围及间质性皮炎,伴有吞噬弹性纤维的巨噬细胞。此外,还观察到局灶性真皮弹性组织离解。迄今为止,包括我们的病例在内,仅报道了3例具有这种特征性临床病理表现的病例。推测该疾病属于真皮中部弹性组织离解临床表现谱。建议将未来的病例归为临时诊断“伴有局灶性真皮中部弹性组织吞噬的网状红斑”(REMDE),以更深入了解这种罕见疾病。