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表现为持续性网状红斑的真皮中层弹性组织吞噬现象。

Mid-dermal elastophagocytosis presenting as a persistent reticulate erythema.

作者信息

Bannister M J, Rubel D M, Kossard S

机构信息

Skin and Cancer Foundation Australia, Sydney, New South Wales, Australia.

出版信息

Australas J Dermatol. 2001 Feb;42(1):50-4. doi: 10.1046/j.1440-0960.2001.00474.x.

Abstract

Two men are presented with a widespread persistent reticulate erythema concentrated within the chronically sun-damaged skin on their trunk. A fine papular element was present in one case and both lacked annular lesions. One patient was human immunodeficiency virus positive. Multiple skin biopsies showed an interstitial infiltrate of histiocytes containing multiple elastic fibres in the upper dermis. There was scant perivascular lymphocytic inflammation but no evident necrobiosis or palisaded granulomas seen typically with granuloma annulare. Elastic stains showed focal mid-dermal elastolysis. Diffuse reticulate erythema in sun-damaged skin may be a clinical marker for elastophagocytosis. This presentation differs from that previously described with actinic granuloma, diffuse granuloma annulare or the inflammatory phase of mid-dermal elastolysis and expands the clinical spectrum of this phenomenon.

摘要

两名男性患者躯干上长期受阳光损伤的皮肤出现广泛持续性网状红斑。其中一例有细小丘疹成分,两例均无环状损害。一名患者人类免疫缺陷病毒呈阳性。多次皮肤活检显示,真皮上层有组织细胞间质浸润,内含多条弹性纤维。血管周围淋巴细胞炎症轻微,但未见典型环状肉芽肿的明显渐进性坏死或栅栏状肉芽肿。弹性染色显示真皮中层局灶性弹性组织离解。阳光损伤皮肤中的弥漫性网状红斑可能是弹性组织吞噬作用的临床标志。这种表现与先前描述的光化性肉芽肿、弥漫性环状肉芽肿或真皮中层弹性组织离解的炎症期不同,扩展了这一现象的临床谱。

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