Kivistö Juho E, Arvola Taina, Parkkari Jari, Mattila Ville M
School of Public Health, University of Tampere, Finland.
Acta Paediatr. 2008 Jun;97(6):790-4. doi: 10.1111/j.1651-2227.2008.00771.x. Epub 2008 Apr 7.
Acute poisonings are a major cause of morbidity among children. This study aims to describe the incidence and nature of emergency visits for acute paediatric poisoning among Finnish children.
All patients younger than 16 years admitted to the Tampere University Hospital's emergency department with a diagnosis of poisoning during 2002-2006 were identified from the Hospital Information System using the International Classification of Diseases (ICD-10).
Altogether 369 emergency visits were diagnosed with poisoning, the overall incidence being 8.1 per 10 000 person-years (95% CI 7.3-9.0). A majority of patients were adolescents aged 10-15 years (48%) and children under 5 years (45%). Boys represented 55% of the cases. Nonpharmaceutical agents were suspected to be the cause in 60.4% and pharmaceuticals in 30.6% of the intoxications. Multiple agents were involved in 8.4% of the cases. Ethanol was the agent in 30.9% of the poisonings. Most patients (78.9%) were hospitalized (median length of stay 1 day). Overall mortality was 0.3%.
Acute paediatric poisonings represent a relatively frequent problem in Finland, and remain a life-threatening problem. The high proportion of alcohol poisonings highlights the necessity to develop more effective primary prevention programs.
急性中毒是儿童发病的主要原因。本研究旨在描述芬兰儿童急性中毒急诊就诊的发生率和性质。
利用国际疾病分类(ICD - 10),从医院信息系统中识别出2002 - 2006年期间因中毒诊断而入住坦佩雷大学医院急诊科的所有16岁以下患者。
共诊断出369例中毒急诊就诊病例,总发病率为每10000人年8.1例(95%可信区间7.3 - 9.0)。大多数患者为10 - 15岁青少年(48%)和5岁以下儿童(45%)。男孩占病例的55%。60.4%的中毒病例怀疑是非药物制剂所致,30.6%是药物所致。8.4%的病例涉及多种制剂。30.9%的中毒病例是由乙醇引起的。大多数患者(78.9%)住院治疗(中位住院时间1天)。总体死亡率为0.3%。
急性儿童中毒在芬兰是一个相对常见的问题,仍然是一个危及生命的问题。酒精中毒比例高凸显了制定更有效一级预防方案的必要性。