交感神经切除大鼠的副交感神经对心脏的影响。

Parasympathetic cardiac effects in sympathectomized rats.

作者信息

Gizzatullin A R, Gilmutdinova R I, Minnahmetov R R, Sitdikov F G, Chiglintcev V M

机构信息

Department of Anatomy, Physiology, and Human Health Protection, Tatar State Humanitarian Pedagogical University, Kazan.

出版信息

Bull Exp Biol Med. 2007 Aug;144(2):166-70. doi: 10.1007/s10517-007-0280-y.

DOI:10.1007/s10517-007-0280-y

PMID:18399271

Abstract

In adult sympathectomized rats the right and left vagus nerves exhibited asymmetric effects on heart rate and strength of cardiac contractions. After vagotomy, the heart rate and stroke volume remained high in sympathectomized rats, but returned to normal in intact animals. The sympathetic nervous system plays a role in postvagotomic tachycardia. Sympathectomized rats were characterized by higher reactivity of cardiac beta-adrenoceptors to propranolol compared to intact animals.

摘要

在成年去交感神经大鼠中，左右迷走神经对心率和心脏收缩强度表现出不对称的影响。切断迷走神经后，去交感神经大鼠的心率和心输出量仍保持在较高水平，但完整动物的心率和心输出量恢复正常。交感神经系统在迷走神经切断术后的心动过速中起作用。与完整动物相比，去交感神经大鼠心脏β-肾上腺素能受体对普萘洛尔的反应性更高。