van Gammeren A J, Cobbaert C M, Schrauwen C J M, Voets M A J, Ermens A A M
Department of Clinical Chemistry and Haematology, Amphia Hospital, The Netherlands.
Transfus Med. 2008 Apr;18(2):134-6. doi: 10.1111/j.1365-3148.2008.00851.x.
An 18-year old woman admitted for tonsillectomy developed prolonged post-operative paralysis after anaesthesia with mivacurium. Investigation revealed a decreased cholinesterase activity because of a homozygous atypical and heterozygous K variant of the cholinesterase gene. Transfusion of fresh frozen plasma was associated with reversal of the respiratory paralysis and complete recovery.