Sharma S, Bhagwat A R, Loya Y S
Department of Cardiology, BYL Nair Hospital and TN Medical College, Bombay.
J Assoc Physicians India. 1991 Aug;39(8):610-3.
We performed balloon angioplasty (BA) in 12 patients with native coarctation of the aorta (COA), aged 2-32 years (average 20.7). The peak systolic gradient across the COA segment decreased from 60.75 +/- 21.85 to 15.66 +/- 9.44 mmHg (p less than 0.001) after the procedure. Angiographically all had more than 50% increase in the diameter of the narrowed segment. During clinical follow up (2.42 months post procedure), all had marked symptomatic benefit. Follow up by haemodynamics and angiography in 4 cases (average 7.7 months post BA) and by echo-doppler in 2 cases (3.6 months post BA) revealed no evidence of aneurysm or restenosis. Our results indicate that BA is a simple, safe, nonoperative alternative to surgery in COA. The immediate and intermediate follow up results are encouraging; however, long term studies are needed to define the true incidence of restenosis and aneurysm.
我们对12例年龄在2至32岁（平均20.7岁）的先天性主动脉缩窄（COA）患者进行了球囊血管成形术（BA）。术后，跨COA节段的收缩期峰值压差从60.75±21.85 mmHg降至15.66±9.44 mmHg（p<0.001）。血管造影显示，所有患者狭窄节段的直径均增加了50%以上。在临床随访期间（术后2.42个月），所有患者的症状均有明显改善。4例患者（BA术后平均7.7个月）通过血流动力学和血管造影进行随访，2例患者（BA术后3.6个月）通过超声多普勒进行随访，均未发现动脉瘤或再狭窄的迹象。我们的结果表明，对于COA，BA是一种简单、安全的非手术治疗方法，可替代手术治疗。近期和中期随访结果令人鼓舞；然而，需要进行长期研究以确定再狭窄和动脉瘤的真实发生率。
