Sharma S, Bhagwat A R, Loya Y S
Department of Cardiology, BYL Nair Hospital and TN Medical College, Bombay.
J Assoc Physicians India. 1991 Aug;39(8):610-3.
We performed balloon angioplasty (BA) in 12 patients with native coarctation of the aorta (COA), aged 2-32 years (average 20.7). The peak systolic gradient across the COA segment decreased from 60.75 +/- 21.85 to 15.66 +/- 9.44 mmHg (p less than 0.001) after the procedure. Angiographically all had more than 50% increase in the diameter of the narrowed segment. During clinical follow up (2.42 months post procedure), all had marked symptomatic benefit. Follow up by haemodynamics and angiography in 4 cases (average 7.7 months post BA) and by echo-doppler in 2 cases (3.6 months post BA) revealed no evidence of aneurysm or restenosis. Our results indicate that BA is a simple, safe, nonoperative alternative to surgery in COA. The immediate and intermediate follow up results are encouraging; however, long term studies are needed to define the true incidence of restenosis and aneurysm.
我们对12例年龄在2至32岁(平均20.7岁)的先天性主动脉缩窄(COA)患者进行了球囊血管成形术(BA)。术后,跨COA节段的收缩期峰值压差从60.75±21.85 mmHg降至15.66±9.44 mmHg(p<0.001)。血管造影显示,所有患者狭窄节段的直径均增加了50%以上。在临床随访期间(术后2.42个月),所有患者的症状均有明显改善。4例患者(BA术后平均7.7个月)通过血流动力学和血管造影进行随访,2例患者(BA术后3.6个月)通过超声多普勒进行随访,均未发现动脉瘤或再狭窄的迹象。我们的结果表明,对于COA,BA是一种简单、安全的非手术治疗方法,可替代手术治疗。近期和中期随访结果令人鼓舞;然而,需要进行长期研究以确定再狭窄和动脉瘤的真实发生率。