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BCR/ABL promotes accumulation of chromosomal aberrations induced by oxidative and genotoxic stress.

作者信息

Koptyra M, Cramer K, Slupianek A, Richardson C, Skorski T

出版信息

Leukemia. 2008 Oct;22(10):1969-72. doi: 10.1038/leu.2008.78. Epub 2008 Apr 10.

DOI:10.1038/leu.2008.78
PMID:18401418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3857962/
Abstract
摘要

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Clinical and pathologic analysis of 16 cases of relapsed chronic myeloid leukemia after stem cell transplantation.16例干细胞移植后复发慢性髓系白血病的临床与病理分析
Am J Clin Pathol. 2007 Oct;128(4):565-70. doi: 10.1309/ECDWCRLG889K1GGD.
2
The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in philadelphia chromosome-negative cells.费城染色体阴性细胞中存在克隆性细胞遗传学异常的慢性髓性白血病患者的预后。
Cancer. 2007 Oct 1;110(7):1509-19. doi: 10.1002/cncr.22936.
3
Chromosomal abnormalities in Philadelphia chromosome negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase.在新诊断的慢性期慢性髓性白血病患者甲磺酸伊马替尼治疗期间出现的费城染色体阴性中期的染色体异常。
Blood. 2007 Oct 15;110(8):2991-5. doi: 10.1182/blood-2007-01-070045. Epub 2007 Jul 11.
4
Leukemia stem cells in a genetically defined murine model of blast-crisis CML.在基因定义的急变期慢性粒细胞白血病小鼠模型中的白血病干细胞。
Blood. 2007 Oct 1;110(7):2578-85. doi: 10.1182/blood-2007-02-073031. Epub 2007 Jun 29.
5
Dynamics of cytogenetic aberrations in Philadelphia chromosome positive and negative hematopoiesis during dasatinib therapy of chronic myeloid leukemia patients after imatinib failure.达沙替尼治疗伊马替尼治疗失败的慢性髓性白血病患者过程中费城染色体阳性和阴性造血的细胞遗传学畸变动态变化
Haematologica. 2007 Jun;92(6):834-7. doi: 10.3324/haematol.11064.
6
Chronic myeloid leukaemia as a model of disease evolution in human cancer.慢性髓性白血病作为人类癌症疾病演变的模型。
Nat Rev Cancer. 2007 Jun;7(6):441-53. doi: 10.1038/nrc2147.
7
Fusion tyrosine kinases: a result and cause of genomic instability.融合酪氨酸激酶：基因组不稳定的结果与原因。
Oncogene. 2007 Jan 4;26(1):11-20. doi: 10.1038/sj.onc.1209756. Epub 2006 Jun 19.
8
ATR-Chk1 axis protects BCR/ABL leukemia cells from the lethal effect of DNA double-strand breaks.ATR-Chk1轴可保护BCR/ABL白血病细胞免受DNA双链断裂的致死效应。
Cell Cycle. 2006 May;5(9):994-1000. doi: 10.4161/cc.5.9.2722. Epub 2006 May 1.
9
BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance.BCR/ABL激酶通过活性氧诱导自身诱变以编码伊马替尼抗性。
Blood. 2006 Jul 1;108(1):319-27. doi: 10.1182/blood-2005-07-2815. Epub 2006 Mar 9.
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BCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells.BCR/ABL改变造血细胞中DNA双链断裂修复的动力学和保真度。
DNA Repair (Amst). 2006 Feb 3;5(2):243-50. doi: 10.1016/j.dnarep.2005.10.005. Epub 2005 Nov 16.