Peralta-Torres Nancy María, Trujillo-Benavides Omar Edel, Paredes-Cruz Enrique, Méndez-del Monte Reyna, Baltazar-Montúfar Pablo de Jesús
Servicio de Endoscopia Gastrointestinal, Hospital de Especialidades Dr. Antonio Fraga Mouret Unidad Médica de Alta Especialidad del Centro Médico Nacional La Raza, IMSS, DF Mixico.
Rev Gastroenterol Mex. 2007 Jul-Sep;72(3):214-21.
To determine association between obesity, gastroesophageal reflux symptoms, hiatus hernia and erosive esophagitis.
Consecutive patients who underwent upper endoscopies at our center were studied. Before endoscopy, through a direct interview all subjects were asked to complete the Carlsson-Dent questionnaire. Weight and height of all patients were determined. Body mass index was calculated. At endoscopy it was looked for the presence of hiatus hernia and erosive esofagitis. We excluded patients with some of the following conditions: Pregnancy, ascitis, esophageal varices, esophageal, gastric or duodenal stenosis, and patient who required an emergency or therapeutic endoscopy. We compared prevalence of symptomatic GERD, hiatus hernia and erosive esophagitis between normal weight patients, overweight and obese.
A total of 196 patients were included for analysis, 122 women and 74 men, mean age 52.5 years, 40.3% were overweight and 28.1% were obese. There were 124 patients (63.3%) with symptoms of GERD determined by the C-D Questionnaire obtained. Hiatus hernia was observed in 87 patients (44.4%), and erosive esophagitis in 69 patients (35.7%). Prevalence of GERD symptoms in obese or overweight patients were similar to those normal-weight patients (66.4% and 56.5% respectively, p = 0.20) OR 1.52 (IC 95%, 0.82-2.82). Among obese or overweight hiatus hernia was observed in 47% compared to 38.7% of those normal-weight (p = 0.28) OR 1.40 (IC 95%, 0.76-2.59). Prevalence of erosive esofagitis was also similar in both groups 37.3% and 32.3% respectively (p = 0.52) OR 1.25 (IC 95%, 0.66-2.36).
This study didn't show association between symptoms of GERD, hiatus hernia or erosive esofagitis and overweight or obesity.
确定肥胖、胃食管反流症状、食管裂孔疝和糜烂性食管炎之间的关联。
对在我们中心接受上消化道内镜检查的连续患者进行研究。在内镜检查前,通过直接访谈让所有受试者完成卡尔森 - 登特问卷。测定所有患者的体重和身高,计算体重指数。在内镜检查时,检查是否存在食管裂孔疝和糜烂性食管炎。我们排除了患有以下某些疾病的患者:妊娠、腹水、食管静脉曲张、食管、胃或十二指肠狭窄,以及需要急诊或治疗性内镜检查的患者。我们比较了正常体重患者、超重和肥胖患者中症状性胃食管反流病、食管裂孔疝和糜烂性食管炎的患病率。
共有196例患者纳入分析,其中女性122例,男性74例,平均年龄52.5岁,40.3%为超重,28.1%为肥胖。通过C - D问卷确定有124例患者(63.3%)有胃食管反流病症状。观察到87例患者(44.4%)有食管裂孔疝,69例患者(35.7%)有糜烂性食管炎。肥胖或超重患者中胃食管反流病症状的患病率与正常体重患者相似(分别为66.4%和56.5%,p = 0.20),比值比为1.52(95%可信区间,0.82 - 2.82)。肥胖或超重患者中观察到食管裂孔疝的比例为47%,而正常体重患者为38.7%(p = 0.28),比值比为1.40(95%可信区间,0.76 - 2.59)。两组中糜烂性食管炎的患病率也相似,分别为37.3%和32.3%(p = 0.52),比值比为1.25(95%可信区间,0.66 - 2.36)。
本研究未显示胃食管反流病症状、食管裂孔疝或糜烂性食管炎与超重或肥胖之间存在关联。