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[荷兰全科医生学院的实践指南《儿童哮喘》(第二次修订版);来自儿科肺病学视角的回应]

[The practice guideline 'Asthma in children' (second revision) from the Dutch College of General Practitioners; a response from the perspective of paediatric pulmonology].

作者信息

de Jongste J C

机构信息

Erasmus MC-Sophia Kinderziekenhuis, afd. Kindergeneeskunde, Postbus 2060, 3000 CB Rotterdam.

出版信息

Ned Tijdschr Geneeskd. 2008 Mar 8;152(10):543-5.

Abstract

The second revised guideline 'Asthma in children' from the Dutch College of General Practitioners provides a well-documented and useful overview. Diagnostic recommendations depend heavily on the symptom 'wheezing', which may be difficult to detect in young children. A uniform therapeutic approach for the various asthma phenotypes is recommended, including a therapeutic trial with inhaled corticosteroids for persistent symptoms. Pitfalls include the fact that inhalation of corticosteroids is sometimes difficult in young children, and that the use of corticosteroids in children with transient virus-induced wheeze is not evidence-based. The guideline no longer recommends the use of cromoglycate. Children who are refractory to inhaled steroids should be referred to a paediatrician before trying long-acting beta2-sympathomimetics or leukotriene antagonists. The current challenge is to effectively incorporate this new guideline into a coherent system of care for the asthmatic child in cooperation with paediatricians, asthma nurses and others involved in the diagnosis and treatment of childhood asthma.

摘要

荷兰全科医生学院发布的第二版修订指南《儿童哮喘》提供了一份资料详实且实用的概述。诊断建议在很大程度上依赖于“喘息”症状,而这一症状在幼儿中可能难以察觉。对于各种哮喘表型,推荐采用统一的治疗方法,包括对持续性症状进行吸入性糖皮质激素治疗试验。存在的问题包括,幼儿有时难以吸入糖皮质激素,以及在患有短暂性病毒诱发喘息的儿童中使用糖皮质激素缺乏循证依据。该指南不再推荐使用色甘酸。对吸入性类固醇难治的儿童,在尝试长效β2受体激动剂或白三烯拮抗剂之前,应转诊至儿科医生处。当前的挑战是,与儿科医生、哮喘护理人员及其他参与儿童哮喘诊断和治疗的人员合作,有效地将这一新指南纳入针对哮喘儿童的连贯护理体系。

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