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[组胺是否参与糖尿病眼部并发症?]

[Does histamine participate in diabetic ocular complications?].

作者信息

Grałek M, Fogel W, Chmielecki C

机构信息

Oddziału Okulistyki Pomnika-Szpitala Centrum Zdrowia Matki Polki, Lodzi, Poland.

出版信息

Klin Oczna. 1991 Dec;93(12):337-9.

PMID:1840276
Abstract

The survey presents the results of clinical observation of the visual system and the evaluation of the level of histamine in the retina and choroid (together) and in the lens in poststreptozotocinic diabetes in Wistar tribe rats. The eye fundus exhibited vascular changes of various intensity, also opacities of the lenses were detected. In the chorio-retinal pool and in the lenses of diabetic animals the authors found an increase of the level of histamine in comparison with the control group. The investigations suggest that histamine could be the factor initiating the changes in the permeability of the blood vessels.

摘要

该调查展示了对Wistar大鼠链脲佐菌素诱导糖尿病模型视觉系统的临床观察结果,以及对视网膜和脉络膜(合在一起)和晶状体中组胺水平的评估。眼底呈现出不同强度的血管变化,还检测到晶状体混浊。与对照组相比,作者发现糖尿病动物的脉络膜视网膜池和晶状体中组胺水平升高。研究表明,组胺可能是引发血管通透性变化的因素。

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