Davis Daniel P, Peay Jeremy, Good Benjamin, Sise Michael J, Kennedy Frank, Eastman A Brent, Velky Thomas, Hoyt David B
Divisions of Trauma, University of California, San Diego, California, USA.
J Trauma. 2008 Apr;64(4):889-97. doi: 10.1097/TA.0b013e318148569a.
The role of air medicine in traumatic brain injury (TBI) has been studied extensively using trauma registries but remains unclear. Learning algorithms, such as artificial neural networks (ANN), support vector machines (SVM), and decision trees, can identify relationships between data set variables but are not empirically useful for hypothesis testing.
To use ANN, SVM, and decision trees to explore the role of air medicine in TBI.
Patients with Head Abbreviated Injury Score 3+ were identified from our county trauma registry. Predictive models were generated using ANN, SVM, and decision trees. The three best-performing ANN models were used to calculate differential survival values (actual and predicted outcome) for each patient. In addition, predicted survival values with transport mode artificially input as "air" or "ground" were calculated for each patient to identify those who benefit from air transport. For SVM analysis, chi was used to compare the ratio of unexpected survivors to unexpected deaths for air- and ground-transported patients. Finally, decision tree analysis was used to explore the indications for various transport modes in optimized survival algorithms.
A total of 11,961 patients were included. All three learning algorithms predicted a survival benefit with air transport across all patients, especially those with higher Head Abbreviated Injury Score or Injury Severity Score values, lower Glasgow Coma Scale scores, or hypotension.
Air medical response in TBI seems to confer a survival advantage, especially in more critically injured patients.
利用创伤登记系统对空中医疗在创伤性脑损伤(TBI)中的作用进行了广泛研究,但仍不明确。学习算法,如人工神经网络(ANN)、支持向量机(SVM)和决策树,可以识别数据集变量之间的关系,但在实证检验假设方面并无实际用处。
使用人工神经网络、支持向量机和决策树来探究空中医疗在创伤性脑损伤中的作用。
从我们县的创伤登记系统中识别出头部简略损伤评分3+的患者。使用人工神经网络、支持向量机和决策树生成预测模型。使用三个表现最佳的人工神经网络模型计算每位患者的差异生存值(实际和预测结果)。此外,为每位患者计算人工输入运输方式为“空中”或“地面”时的预测生存值,以确定那些从空中运输中受益的患者。对于支持向量机分析,使用卡方检验比较空中和地面运输患者中意外幸存者与意外死亡者的比例。最后,使用决策树分析在优化生存算法中探索各种运输方式的指征。
共纳入11961例患者。所有三种学习算法均预测空中运输对所有患者均有生存益处,尤其是那些头部简略损伤评分或损伤严重程度评分较高、格拉斯哥昏迷量表评分较低或有低血压的患者。
创伤性脑损伤中的空中医疗响应似乎具有生存优势,尤其是在伤情更严重的患者中。