Luo Fei, Wang Jin-Yan
Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 10A Datun Road, Chaoyang District, Beijing 100101, People's Republic of China.
Neurochem Res. 2008 Oct;33(10):1950-5. doi: 10.1007/s11064-008-9692-y. Epub 2008 Apr 11.
It is universally accepted that acupuncture or acupoint stimulation can produce analgesic effect on patients with painful disorders. The past decades has seen remarkable progress in exploring the central mechanisms of acupuncture-induced pain relief, including the neurotransmitter release and expression of particular receptors and genes in the spinal cord and the brain stem regions. Development of new techniques makes it possible to record and image the brain network patterns underlying pain perception and modulation, and to investigate the role of higher-level brain areas in mediating acupuncture analgesia. This review will present the current understanding of the neural network that is implicated in the modulation of pain by acupuncture.
普遍认为，针灸或穴位刺激对疼痛性疾病患者可产生镇痛作用。在过去几十年中，在探索针刺镇痛的中枢机制方面取得了显著进展，包括脊髓和脑干区域神经递质的释放以及特定受体和基因的表达。新技术的发展使记录和成像疼痛感知和调节背后的脑网络模式以及研究高级脑区在介导针刺镇痛中的作用成为可能。本综述将介绍目前对参与针刺调节疼痛的神经网络的理解。
