Twenty-five years of tendon and ligament research.

Twenty-five years ago, the Journal of Orthopaedic Research published its first volume, which included five articles covering topics in tendon and ligament research. Since then, the body of tendon and ligament research has continued to increase exponentially. This review summarizes major advancements in tendon and ligament research since the initial publication of this journal. The purpose of this article is not to provide an in-depth review of all of tendon and ligament research, but instead to provide a concise literature review of some of the major and recurring areas of research. The general topics covered over the last 25 years include tissue properties, tendinopathy, healing, and engineered scaffolds.