Ezzyat Youssef, Olson Ingrid R
University ofPennsylvania, Philadelphia, Pennsylvania, USA.
Cogn Affect Behav Neurosci. 2008 Mar;8(1):32-40. doi: 10.3758/cabn.8.1.32.
Whether the hippocampus and medial temporal lobe (MTL) play any important role in visual working memory is a relatively new and controversial research question. The primary goal of this study was to assess working memory for faces over very short delays in patients with MTL damage. Patients and matched controls were required to remember one face that was parametrically morphed to be more or less similar to a probe face, over either a 1- or an 8-sec delay. Memory was assessed using both forced choice and old-new recognition tasks. The results show that MTL damage impairs both speed and accuracy of visual working memory across tasks. We speculate that the hippocampus is generally necessary for memory encoding.
海马体和内侧颞叶（MTL）在视觉工作记忆中是否发挥任何重要作用是一个相对较新且有争议的研究问题。本研究的主要目的是评估MTL损伤患者在极短延迟时间内对面孔的工作记忆。要求患者和匹配的对照组在1秒或8秒的延迟时间内记住一张通过参数变形使其与探测面孔或多或少相似的面孔。使用强制选择和新旧识别任务来评估记忆。结果表明，MTL损伤会损害跨任务视觉工作记忆的速度和准确性。我们推测，海马体对于记忆编码通常是必需的。
