Stockbridge Eva Boné, Deleuran Mette Søndergaard, Steiniche Torben
Arhus Universitetshospital, Arhus Sygehus, Dermatologisk Afdeling S, Arhus C.
Ugeskr Laeger. 2008 Mar 31;170(14):1158.
A 7-year-old girl of Colombian descent was referred for diagnosis and treatment. She initially presented signs of universal itchy eczema in the spring of 2003. She responded to local treatment with topical steroids, but her symptoms rapidly re-emerged after discharge. Further investigations led to the conclusion that the patient suffered from Actinic Prurigo. The disease was very severe and there was a lack of response to treatment with oral prednisolone, antihistamines and pentoxyfyllin. Therefore the patient was treated with Thalidomide 50 mg/25 mg daily (alternating). This resulted in the complete clearance of her skin symptoms except postinflammatory hyperpigmentation.
一名7岁的哥伦比亚裔女孩前来接受诊断和治疗。她最初于2003年春季出现全身性瘙痒性湿疹症状。局部使用类固醇治疗后症状有所缓解,但出院后症状迅速复发。进一步检查后得出结论,该患者患有光化性痒疹。病情非常严重,口服泼尼松龙、抗组胺药和己酮可可碱治疗均无效果。因此,给予患者沙利度胺治疗,每日50 mg/25 mg(交替服用)。治疗后除炎症后色素沉着外,皮肤症状完全消失。