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[使用微型体外循环系统的冠状动脉搭桥手术:一家西班牙单位的经验]

[Coronary artery bypass surgery using the mini-extracorporeal circulation system: a Spanish unit's experience].

作者信息

Zamora Elisabet, Delgado Luis, Castro Miguel A, Fernández Mireia, Orrit Javier, Romero Bernat, Cámara Maria L, Ruyra Xavier

机构信息

Servicio de Cardiología. Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, España.

出版信息

Rev Esp Cardiol. 2008 Apr;61(4):376-81.

Abstract

INTRODUCTION AND OBJECTIVES

The increasing use of percutaneous interventions has resulted in a significant reduction in coronary artery bypass grafting. Today, patients referred for surgery are older, have more comorbidities, and have undergone previous percutaneous intervention, and their ventricular function is poorer. As a result, surgery has attempted to improve its results by adopting a number of different strategies. The aim of this study was to investigate and describe one cardiac surgery unit's initial experience with coronary artery bypass grafting using mini-extracorporeal circulation (MECC), which had become its technique of choice.

METHODS

A retrospective analysis of 408 patients who underwent isolated coronary artery bypass grafting using MECC between January 2004 and April 2007 was carried out. Of the 408, 329 (80.6%) were men, their mean age was 63.5 years (28-83 years), 63% had hypertension, 49.3% had diabetes, 69% had hyperlipidemia, and 52% were smokers.

RESULTS

The surgical mortality rate predicted by the logistic EuroSCORE was 3.7% (range, 1-38). Overall, 34% of patients had left main coronary artery disease and 87% had three-vessel disease. In 74%, complete revascularization was carried out using a mean of 2.97 (range, 1-7) grafts per patient. A mammary artery graft was used in all cases. The in-hospital mortality rate was 0.74%. There were few postoperative complications: 0.98% of patients required further surgery because of bleeding, 3.4% had a significantly elevated troponin-I level, 6.4% developed kidney failure, and 0.5% suffered a stroke.

CONCLUSIONS

Coronary artery bypass grafting using MECC enabled complete revascularization to be performed in most patients, and morbidity and mortality rates were low.

摘要

引言与目的

经皮介入治疗的使用日益增加,导致冠状动脉旁路移植术显著减少。如今,接受手术治疗的患者年龄更大,合并症更多,且曾接受过经皮介入治疗,其心室功能较差。因此,外科手术试图通过采用多种不同策略来改善手术效果。本研究的目的是调查并描述一个心脏外科单元使用微创体外循环(MECC)进行冠状动脉旁路移植术的初步经验,MECC已成为其首选技术。

方法

对2004年1月至2007年4月间使用MECC进行单纯冠状动脉旁路移植术的408例患者进行回顾性分析。在这408例患者中,329例(80.6%)为男性,平均年龄为63.5岁(28 - 83岁),63%患有高血压,49.3%患有糖尿病,69%患有高脂血症,52%为吸烟者。

结果

经逻辑EuroSCORE预测的手术死亡率为3.7%(范围为1 - 38)。总体而言,34%的患者患有左主干冠状动脉疾病,87%患有三支血管疾病。74%的患者实现了完全血运重建,每位患者平均使用2.97支(范围为1 - 7支)移植血管。所有病例均使用了乳内动脉移植血管。住院死亡率为0.74%。术后并发症较少:0.98%的患者因出血需要再次手术,3.4%的患者肌钙蛋白I水平显著升高,6.4%的患者出现肾衰竭,0.5%的患者发生中风。

结论

使用MECC进行冠状动脉旁路移植术能够使大多数患者实现完全血运重建,且发病率和死亡率较低。

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