Losasso Thomas
Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Int J Radiat Oncol Biol Phys. 2008;71(1 Suppl):S85-8. doi: 10.1016/j.ijrobp.2007.06.082.
The use of a multileaf collimator (MLC) for intensity-modulated radiotherapy poses unique dosimetric issues. The nature of intensity-modulated radiotherapy dosimetry, centered on leaf position accuracy, is common to all MLCs. However, the mechanical and software designs of MLCs from the different manufacturers distinguish them. This report focused on the Varian Millennium 120, although the concepts are applicable to the earlier Varian Mark series as well. The factors that affect dose delivery in clinical fields (i.e., mechanical tolerances, motor fatigue, and latency effects) have been quantified. Moreover, inadequate modeling of the MLC in the planning system can be perceived as erratic performance. Individually, some problems have been shown to be insignificant; others are correctable using software. If these problems are rectified or at least understood by the physicist, quality assurance can be simplified.
在调强放射治疗中使用多叶准直器(MLC)会带来独特的剂量学问题。以叶片位置精度为核心的调强放射治疗剂量学特性,对所有MLC来说都是共有的。然而,不同制造商生产的MLC在机械和软件设计上存在差异。本报告重点关注瓦里安Millennium 120,尽管这些概念同样适用于早期的瓦里安Mark系列。已对影响临床射野剂量传递的因素(即机械公差、电机疲劳和延迟效应)进行了量化。此外,计划系统中MLC建模不足可能会被视为性能不稳定。个别情况下,一些问题已被证明微不足道;其他问题可通过软件进行校正。如果物理学家能够纠正这些问题或至少理解这些问题,质量保证工作就可以简化。