碘缺乏症的流行病学。
Epidemiology of iodine deficiency.
机构信息
Eduardo Gaitan is at the Department of Medicine, University of Mississippi Medical School, Endocrinology Section, Veterans Affairs Medical Center, Jackson, MS 39216, USA.
出版信息
Trends Endocrinol Metab. 1992 Jul;3(5):170-5. doi: 10.1016/1043-2760(92)90167-y.
Iodine deficiency (ID) causes goiter, cretinism, neonatal hypothyroidism, irreversible mental retardation, and child and infant death. Over one billion people are at risk, most of them in developing countries. While ID is the primordial factor in these conditions, other environmental and host factors significantly modify the magnitude and clinical presentation of iodine deficiency disorders. The interactions and mechanisms by which these factors operate are complex and mostly unknown, requiring more investigation.
碘缺乏（ID）可导致甲状腺肿、克汀病、新生儿甲状腺功能减退、不可逆转的智力障碍以及儿童和婴儿死亡。全球有超过 10 亿人面临碘缺乏的威胁，其中大多数生活在发展中国家。尽管碘缺乏是这些疾病的主要因素，但其他环境和宿主因素也会显著改变碘缺乏症的严重程度和临床表现。这些因素的相互作用和作用机制非常复杂，大部分仍不为人知，需要进一步研究。
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