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利用特异性、敏感性和挽救的生命数量评估公共卫生监测的效用。

Assessing the utility of public health surveillance using specificity, sensitivity, and lives saved.

作者信息

Kleinman Ken P, Abrams Allyson M

机构信息

Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA.

出版信息

Stat Med. 2008 Sep 10;27(20):4057-68. doi: 10.1002/sim.3269.

DOI:10.1002/sim.3269
PMID:18407576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2553710/
Abstract

In modern surveillance of public health, data may be reported in a timely fashion and include spatial data on cases in addition to the time of their occurrence. This has lead to many recent developments in statistical methods to detect events of public health importance. However, there has been relatively little work about how to compare such methods. One powerful rationale for performing surveillance is earlier detection of events of public health significance; previous evaluation tools have focused on metrics that include the timeliness of detection in addition to sensitivity and specificity. However, such metrics have not accounted for the number of persons affected by the events. We re-examine the rationale for this surveillance and conclude that earlier detection is preferred because it can prevent additional morbidity and mortality. On the basis this observation, we propose evaluating the number of cases prevented by each detection method, and include this information in assessing the value of different detection methods. Using this approach incorporates more information about the events and the detection and provides a sound basis for making decisions about which detection methods to employ.

摘要

在现代公共卫生监测中,数据可能会及时上报,除了事件发生时间外,还包括病例的空间数据。这促使了统计方法在检测具有公共卫生重要性的事件方面取得了许多最新进展。然而,关于如何比较这些方法的研究相对较少。进行监测的一个有力理由是更早地发现具有公共卫生意义的事件;以前的评估工具关注的指标除了敏感性和特异性外,还包括检测的及时性。然而,这些指标没有考虑受事件影响的人数。我们重新审视了这种监测的理由,并得出结论,更早发现是可取的,因为它可以预防额外的发病和死亡。基于这一观察结果,我们建议评估每种检测方法预防的病例数,并将此信息纳入评估不同检测方法的价值中。使用这种方法可以纳入更多关于事件和检测的信息,并为决定采用哪种检测方法提供合理依据。

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本文引用的文献

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Assessing surveillance using sensitivity, specificity and timeliness.使用敏感性、特异性和及时性评估监测。
Stat Methods Med Res. 2006 Oct;15(5):445-64. doi: 10.1177/0962280206071641.
3
Evaluating spatial surveillance: detection of known outbreaks in real data.评估空间监测:在真实数据中检测已知疫情
Stat Med. 2006 Mar 15;25(5):755-69. doi: 10.1002/sim.2402.
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Simulation for assessing statistical methods of biologic terrorism surveillance.用于评估生物恐怖主义监测统计方法的模拟
MMWR Suppl. 2005 Aug 26;54:101-8.
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A model-adjusted space-time scan statistic with an application to syndromic surveillance.一种模型调整后的时空扫描统计量及其在症状监测中的应用。
Epidemiol Infect. 2005 Jun;133(3):409-19. doi: 10.1017/s0950268804003528.
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A space-time permutation scan statistic for disease outbreak detection.用于疾病爆发检测的时空置换扫描统计量。
PLoS Med. 2005 Mar;2(3):e59. doi: 10.1371/journal.pmed.0020059. Epub 2005 Feb 15.
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Stat Med. 2005 Feb 28;24(4):543-50. doi: 10.1002/sim.2034.
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