Seike Junichi, Matsuoka Hisashi, Yuasa Yasuhiro, Yamai Hiromichi, Yoshida Takahiro, Honda Junko, Miyoshi Takanori, Tangoku Akira
Department of Oncological and Regenerative Surgery, Institute of Health Bioscience, the University of Tokushima Graduate School.
Gan To Kagaku Ryoho. 2008 Apr;35(4):633-6.
A 64-year-old woman with advanced esophageal cancer underwent chemotherapy with docetaxel/5-FU/CDDP (DFP). Adverse reactions were severe nausea and general fatigue, so the patient decided to discontinue DFP therapy. The treatment was changed to S-1/docetaxel. Adverse reactions were not so severe, so she could receive 1 course of the medication completely. After the treatment, the primary lesion showed a partial response, so we performed surgery. In the resected specimen, no malignant cell could be seen microscopically. Though the advanced esophageal cancer was regarded as a systemic disease, the appropriate combination of chemotherapy and surgery proved effective.
一名64岁的晚期食管癌女性患者接受了多西他赛/5-氟尿嘧啶/顺铂（DFP）化疗。不良反应为严重恶心和全身乏力，因此患者决定停止DFP治疗。治疗改为S-1/多西他赛。不良反应不那么严重，所以她能够完整接受1个疗程的药物治疗。治疗后，原发灶显示部分缓解，于是我们进行了手术。在切除的标本中，显微镜下未见恶性细胞。尽管晚期食管癌被视为一种全身性疾病，但化疗和手术的恰当联合证明是有效的。
