Katsaridis Vasilios, Papagiannaki Chrysanthi, Aimar Enrico
Neurosurgical Department, G Papanikolaou General Hospital, Thessaloniki, Greece.
Neuroradiology. 2008 Jul;50(7):589-97. doi: 10.1007/s00234-008-0382-x. Epub 2008 Apr 12.
Onyx has emerged in the recent years as a new embolic material. We present our experience with Onyx in the curative embolization of brain cerebral arteriovenous malformations (AVMs).
We retrospectively reviewed the files of all patients that we had treated with Onyx embolic material for a brain AVM during the last 4 years. We identified 101 patients who underwent a total of 219 sessions of embolization.
The treatment has been concluded in 52 patients; in this group, total occlusion was obtained in 28 (53.9%) patients and near-total occlusion was obtained in 18 (34.6%). The respective figures based on the 101 patients of the study cohort are 28/101 (27.7%) and 18/101 (17.8%). More embolization sessions are to be carried out on the remaining 49 patients. There were three deaths, and eight patients had permanent neurological deficits with a resulting morbidity of 8% and mortality of 3%.
High rates of total or near-total occlusion of brain AVMs can be achieved with multiple sessions of Onyx embolization with acceptable morbidity and mortality.
近年来，Onyx作为一种新型栓塞材料出现。我们介绍我们使用Onyx治疗脑动静脉畸形（AVM）的经验。
我们回顾性分析了过去4年中所有使用Onyx栓塞材料治疗脑AVM的患者病历。我们确定了101例患者，共进行了219次栓塞治疗。
52例患者完成治疗；在该组中，28例（53.9%）患者实现完全闭塞，18例（34.6%）患者实现近完全闭塞。基于研究队列的101例患者，相应数字分别为28/101（27.7%）和18/101（17.8%）。其余49例患者还需进行更多次栓塞治疗。有3例死亡，8例患者出现永久性神经功能缺损，发病率为8%，死亡率为3%。
通过多次使用Onyx栓塞治疗脑AVM，可实现较高的完全或近完全闭塞率，且发病率和死亡率可接受。
