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盘基网柄菌形态发生过程中细胞分化的调控。

Regulation of cellular differentiation during Dictyostelium morphogenesis.

作者信息

Williams J G

机构信息

Clare Hall Laboratory, Imperial Cancer Research Fund, South Mimms, Herts, UK.

出版信息

Curr Opin Genet Dev. 1991 Oct;1(3):358-62. doi: 10.1016/s0959-437x(05)80300-4.

DOI:10.1016/s0959-437x(05)80300-4
PMID:1840893
Abstract

In Dictyostelium there are multiple prestalk cell types that have a complex pattern of directed cell movement during slug formation and culmination. Three extracellular signals, cyclic AMP, DIF and ammonia, control cell type differentiation. Recently there has been considerable progress in understanding their modes of action and interaction.

摘要

在盘基网柄菌中，有多种前柄细胞类型，它们在蛞蝓体形成和发育成熟过程中具有复杂的定向细胞运动模式。三种细胞外信号，即环磷酸腺苷（cAMP）、分化诱导因子（DIF）和氨，控制着细胞类型的分化。最近，在了解它们的作用方式和相互作用方面取得了相当大的进展。

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CulB, a putative ubiquitin ligase subunit, regulates prestalk cell differentiation and morphogenesis in Dictyostelium spp.CulB是一种假定的泛素连接酶亚基，可调节盘基网柄菌属中的前柄细胞分化和形态发生。
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