Miraglia N, Simonelli A, Basilicata P, Genovese G, Acampora A, Sannolo N
Dipartimento di Medicina Sperimentale, Sezione di Medicina del Lavoro, Igiene e Tossicologia Industriale, Seconda Università degli Studi, Napoli.
G Ital Med Lav Ergon. 2007 Jul-Sep;29(3 Suppl):367-8.
The risk evaluation related to the occupational exposure to hazardous substances can be performed either by analytical data coming from environmental and/or biological monitoring or by using models and mathematical algorithms. Models are often considered economically more advantageous, nevertheless, in order to assure their reliability, they need to be validated by objective monitoring data. A predictive model for the evaluation of risks due to the exposure to pesticides in agriculture was elaborated, and, for model validations, 20 tomato farms were examined. For each farm, information necessary to the risk evaluation by using the elaborated algorithm were collected and, simultaneously, an environmental monitoring for the evaluation of inhaling and cutaneous exposure was carried out. The potential risk was estimated by comparing analytical data from environmental monitoring with respect to ADI (Admissible Daily Intake) values, for each investigated pesticide. Then, the accordance between the potential risk and the risk given by the elaborated model was evaluated and an agreement of 85.6% was found, showing a substantial reliability of the proposed model.
与职业接触有害物质相关的风险评估既可以通过来自环境和/或生物监测的分析数据来进行,也可以通过使用模型和数学算法来进行。模型通常在经济上更具优势,然而,为了确保其可靠性,它们需要通过客观监测数据进行验证。阐述了一个用于评估农业中接触农药所致风险的预测模型,并且为了进行模型验证,对20个番茄农场进行了检查。对于每个农场,收集了使用所阐述算法进行风险评估所需的信息,同时,进行了用于评估吸入和皮肤接触的环境监测。通过将环境监测的分析数据与每种被调查农药的每日允许摄入量(ADI)值进行比较,估算潜在风险。然后,评估潜在风险与所阐述模型给出的风险之间的一致性,发现一致性为85.6%,表明所提出模型具有较高的可靠性。