Koch E, Bogado M, Araya F, Romero T, Díaz C, Manriquez L, Paredes M, Román C, Taylor A, Kirschbaum A
Division of Epidemiology, School of Public Health, Faculty of Medicine, University of Chile, Santiago, Chile.
J Epidemiol Community Health. 2008 May;62(5):461-70. doi: 10.1136/jech.2007.062240.
To find out whether there is an association between parity and obesity, evaluated through body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) in Chilean women after controlling for sociodemographic characteristics, health risk and gynaeco-obstetric factors.
Cross-sectional study, using baseline data of the San Francisco Project.
San Francisco de Mostazal, located in the central region of Chile, 6512 Chilean-Hispanic women (Spanish heritage with a variable indigenous component).
A weighted random sample of 508 women who had their first pregnancy inside the primary child-bearing ages. Data were collected between 1997 and 1999. Statistical associations between parity and different anthropometric measurements of adiposity in multiple linear (MLnR) and logistic regression models (MLtR) were evaluated.
In MLnR a modest parity-related increment in BMI and practically null increment in WC, WHR and WHtR was observed. Covariates that showed a statistically significant association with anthropometric measures of adiposity were age, low education, marital status, employment, smoking, smoking cessation, hypertension, diabetes, dyslipidaemia, parent's obesity, menarche and fetal macrosomia. Crude odds ratio (OR) showed a strong association between parity and anthropometric markers of obesity. Nevertheless, after adjustments in MLtR models, the association remained only for BMI. All the measures of abdominal obesity related to parous women showed OR smaller than 1 (95% confidence intervals 0.57 to 0.96).
Parity modestly influences BMI, but does not seem to be related to WC, WHR and WHtR after controlling by confounders. Parity can increase adiposity but not necessarily following an abdominal pattern.
在控制社会人口学特征、健康风险和妇产科因素后,研究智利女性的生育胎次与肥胖之间是否存在关联,肥胖通过体重指数(BMI)、腰围(WC)、腰臀比(WHR)和腰高比(WHtR)进行评估。
横断面研究,使用旧金山项目的基线数据。
位于智利中部地区的圣弗朗西斯科·德莫斯塔扎尔,6512名智利裔西班牙女性(具有不同程度土著血统的西班牙裔)。
对508名在主要生育年龄内首次怀孕的女性进行加权随机抽样。数据收集于1997年至1999年期间。在多元线性(MLnR)和逻辑回归模型(MLtR)中评估生育胎次与不同肥胖人体测量指标之间的统计关联。
在MLnR中,观察到生育胎次与BMI有适度增加相关,而WC、WHR和WHtR几乎没有增加。与肥胖人体测量指标有统计学显著关联的协变量包括年龄、低教育程度、婚姻状况、就业、吸烟、戒烟、高血压、糖尿病、血脂异常、父母肥胖、初潮和巨大儿。粗比值比(OR)显示生育胎次与肥胖人体测量指标之间有很强的关联。然而,在MLtR模型中进行调整后,这种关联仅在BMI方面仍然存在。所有与经产女性相关的腹部肥胖指标的OR均小于1(95%置信区间为0.57至0.96)。
生育胎次适度影响BMI,但在控制混杂因素后,似乎与WC、WHR和WHtR无关。生育胎次可增加肥胖,但不一定呈腹部肥胖模式。