Donato Giovana B, Fuchs Sandra C, Oppermann Karen, Bastos Carlos, Spritzer Poli Mara
Postgraduate Program in Medicine: Medical Sciences, School of Medicine, Federal University of Rio Grande do Sul, RS, Brazil.
Menopause. 2006 Mar-Apr;13(2):280-5. doi: 10.1097/01.gme.0000177907.32634.ae.
To assess the association between menopause status and central adiposity measured using two different cutoffs of waist circumference and waist-to-hip ratio, while controlling for body mass index and other confounding factors.
Cross-sectional study of a representative population-based sample of 358 women from Passo Fundo, Southern Brazil. Medical students performed standardized interviews and anthropometric measurements under supervision. Menopause status was categorized as premenopausal for those with no change in menstrual frequency or flow; menopause transition for those who had these changes; and postmenopausal after 12 months of amenorrhea or bilateral oophorectomy. Obesity was defined by body mass index (BMI) equal or greater than 30 kg/m, whereas central adiposity was defined as a waist circumference equal or greater than 80 or 88 cm and a waist-to-hip-ratio equal or greater than 0.80 or 0.86.
The anthropometric assessment showed that compared with postmenopausal women, premenopausal women were taller, had a thinner waist circumference, and had a lower waist-to-hip ratio. Postmenopausal women had five times the chance of having central adiposity than premenopausal women, even after controlling for BMI and other confounding factors. Women in the menopause transition had an increased BMI, but there was no independent association with central obesity.
Postmenopausal women are at greater risk of central adiposity as detected by both waist circumference and waist-to-hip ratio.
在控制体重指数及其他混杂因素的同时，评估绝经状态与采用两种不同腰围及腰臀比切点测量的中心性肥胖之间的关联。
对巴西南部帕索丰杜的358名女性进行基于人群的代表性样本横断面研究。医学生在监督下进行标准化访谈和人体测量。绝经状态分类如下：月经频率或经量无变化者为绝经前；有这些变化者为绝经过渡；闭经12个月或双侧卵巢切除术后为绝经后。肥胖定义为体重指数（BMI）等于或大于30kg/m²，而中心性肥胖定义为腰围等于或大于80或88cm以及腰臀比等于或大于0.80或0.86。
人体测量评估显示，与绝经后女性相比，绝经前女性更高，腰围更细，腰臀比更低。即使在控制BMI和其他混杂因素后，绝经后女性出现中心性肥胖的几率是绝经前女性的五倍。处于绝经过渡阶段的女性BMI增加，但与中心性肥胖无独立关联。
通过腰围和腰臀比检测发现，绝经后女性发生中心性肥胖的风险更高。
