Spielmans Glen I, Thielges Shelly A, Dent Amy L, Greenberg Roger P
Department of Psychology, Metropolitan State University, St. Paul, Minnesota 55108, USA.
J Nerv Ment Dis. 2008 Apr;196(4):267-73. doi: 10.1097/NMD.0b013e31816a436b.
Psychiatric medications are frequently advertised in medical journals, yet no study has addressed the veracity of claims made in these advertisements. The present study examined the accuracy of 69 medical journal advertisements for psychiatric medications and the availability of sources cited in these advertisements. Just over half of claims made in advertisements (50.2%) provided no attainable source that could be used to check the veracity of the claim. When sources were attained, they supported the cited claims 65% of the time (95% CI: 61.0-69.1). Claims regarding the efficacy of medications were only supported by obtained cited sources on 53.2% of occasions (95% CI: 46.2-60.2). Attempts to obtain cited data on file from sponsoring drug companies were rarely successful. Given the relatively poor empirical substantiation of claims made in medical journal psychiatric drug advertisements and that most claims provided no attainable sources, increased regulation of such advertising is warranted.
精神科药物常在医学期刊上做广告,但尚无研究探讨这些广告中所做声明的真实性。本研究调查了69则精神科药物医学期刊广告的准确性以及这些广告中所引用来源的可得性。广告中所做声明略超过一半(50.2%)未提供可用于核实声明真实性的可获取来源。当获得来源时,它们在65%的情况下支持所引用的声明(95%置信区间:61.0 - 69.1)。关于药物疗效的声明仅在53.2%的情况下得到所获取引用来源的支持(95%置信区间:46.2 - 60.2)。从赞助制药公司获取存档引用数据的尝试很少成功。鉴于医学期刊精神科药物广告中所做声明的实证依据相对不足,且大多数声明未提供可获取来源,因此有必要加强对此类广告的监管。