Voynova E, Dimitrova S, Naydenova E, Karadjov P
National Centre of Oncology, Medical Academy, Sofia, Bulgaria.
Acta Physiol Pharmacol Bulg. 1991;17(4):50-2.
Primary screening of alcohol extracts of fruits of Maclura aurantiaca (Moraceae) and the overground part of Epilobium hirsutum (Onagraceae) was conducted in order to test the anti-tumour action on models in mice. Applied in doses of 100 mg/kg and 90 mg/kg, Maclura extract increased the life span of the mice by 158 and 152% accordingly in leucosis P-388 and ascitic tumour of Ehrich. In doses of 1 mg/kg and 3 mg/kg the Epilobium extract prolonged the life span of the mice by 156 and 158% accordingly in leucosis P-388 and ascitic tumour of Ehrlich.
为了测试桑橙(桑科)果实和毛脉柳叶菜(柳叶菜科)地上部分的酒精提取物对小鼠模型的抗肿瘤作用,进行了初步筛选。桑橙提取物以100mg/kg和90mg/kg的剂量应用时,在P-388白血病和艾氏腹水瘤模型中,分别使小鼠寿命延长了158%和152%。毛脉柳叶菜提取物以1mg/kg和3mg/kg的剂量应用时,在P-388白血病和艾氏腹水瘤模型中,分别使小鼠寿命延长了156%和158%。