Hermeneit S, Müller M, Terzic A, Rodehorst A, Schamberger M, Böttger T
Klinik für Viszeral-, Thorax- und Gefässchirurgie, Zentrum für minimalinvasive Chirurgie.
Zentralbl Chir. 2008 Apr;133(2):156-63. doi: 10.1055/s-2008-1004739.
Due to the demographic shift in the age structure of the population, increasingly older, multimorbid patients are operated who have a substantially higher risk for the occurrence of intra- and postoperative complications. Apart from the identification of patient-referred, hardly influenceable risk factors, influenceable intraoperative surgical and anesthesiological risk factors have hardly ever been examined. The aim of this investigation was therefore to identify influenceable risk factors for the development of post-operative morbidity.
In a period of 44 months, we performed a laparoscopic colon resection in 157 men and 209 women with a mean age of 63 years. The ASA classification, POSSUM score, status of the anesthesiologist, change of the anesthesiologist, intraoperative monitoring, kind of anaesthesia, fluctuations of blood pressure and pulse during the operation, shock-index > 1, substitution of erythrocyte concentrates and FFPs as well as intraoperative surgical complications were documented prospectively. Postoperative general complications requiring therapy, in particular, cardiac and pulmonal problems as well as surgical complications, in particular, infections and hemorrhages, were documented. The data analysis was performed using the program package SPSS.
Intraoperative monitoring was more frequently used in higher ASA stages, whereas for ASA stage IV no central venous line was used in 17 % and no arterial catheter was placed in 33 %. a similar tendency concerning the POSSUM score could not be determined. Patients cared for by junior surgeons exhibited cardiac complications in 6.7 % and 13.1 % had to be mechanically ventilated postoperatively versus 2 % of cardiac complications and 9 % mechanical ventilation among those managed by specialists. An increase in postoperative complications could also be found when a change in anesthesia took place. During treatment by an assistant in case of emergencies, in cases where intraoperative substitution of erythrocytes or an operation lasting more than two hours, more cardiac complications and a higher rate of mechanical respiration was observed than during treatment by a specialist. A mechanical respiration was significantly more necessary in higher ASA stages (p < 0.01), in an operation lasting more than 2 hours (p < 0.01), in cases with the occurrence of intraoperative bleeding complications (p < 0.01), procedures with a lower status of the anesthesiologist (p < 0.01) and in procedures with a change of the anesthesiologist (p < 0.05).
Factors such as overweight, ASA classification or urgency cannot be changed. Surgical factors such as a standardisation of the operation technique with reduction of the operating time and careful staunching of bleeding can help to reduce postoperative complications. Anesthesiologists can also help by avoiding a change of the anesthesiologist as well as by preference of specialists in patients with higher ASA stages and in emergency cases.
由于人口年龄结构的人口结构转变,接受手术的老年多病患者越来越多,他们发生术中及术后并发症的风险显著更高。除了识别患者自身难以改变的风险因素外,几乎从未研究过可改变的术中手术和麻醉风险因素。因此,本研究的目的是确定术后发病的可改变风险因素。
在44个月的时间里,我们对157名男性和209名女性进行了腹腔镜结肠切除术,平均年龄为63岁。前瞻性记录了美国麻醉医师协会(ASA)分级、简化手术应激评分(POSSUM)、麻醉医生的情况、麻醉医生的更换、术中监测、麻醉类型、手术期间血压和脉搏的波动、休克指数>1、红细胞浓缩液和新鲜冰冻血浆的输注以及术中手术并发症。记录了需要治疗的术后一般并发症,特别是心脏和肺部问题,以及手术并发症,特别是感染和出血。使用SPSS程序包进行数据分析。
在较高的ASA分级中,术中监测的使用更为频繁,而对于ASAⅣ级,17%的患者未使用中心静脉导管,33%的患者未放置动脉导管。关于POSSUM评分,未发现类似趋势。由初级外科医生护理的患者心脏并发症发生率为6.7%,术后需要机械通气的比例为13.1%,而由专科医生管理的患者心脏并发症发生率为2%,机械通气比例为9%。麻醉发生变化时,术后并发症也会增加。在紧急情况下由助手进行治疗、术中输注红细胞或手术持续时间超过两小时的情况下,观察到的心脏并发症和机械通气率高于由专科医生治疗的情况。在较高的ASA分级(p<0.01)、手术持续时间超过2小时(p<0.01)、术中发生出血并发症(p<0.01)、麻醉医生水平较低(p<0.01)以及麻醉医生发生更换(p<0.05)的手术中,机械通气明显更有必要。
超重、ASA分级或手术紧急程度等因素无法改变。手术因素,如手术技术标准化以减少手术时间和仔细止血,有助于减少术后并发症。麻醉医生也可以通过避免更换麻醉医生以及在ASA分级较高的患者和紧急情况下优先选择专科医生来提供帮助。