Desai Fanny, Shah Manoj, Patel Shreedevi, Shukla Shilin N
Shija hospitals and Research Institute, Imphal, Manipur, India.
Indian J Pathol Microbiol. 2008 Jan-Mar;51(1):88-90. doi: 10.4103/0377-4929.40413.
The main aim of the study is to evaluate the computed tomography (CT)-guided fine needle aspiration cytology (FNAC) of anterior mediastinal mass as a diagnostic procedure.
In all 135 cases, the material was obtained by CT-guided FNAC technique followed by staining with Papanicolaou and May-Grunwald-Giemsa stains. The histological material was obtained by needle biopsies, wedge biopsies and resection specimens. Immunohistochemical stains were used to confirm diagnosis in selected cases.
Among 135 cases, cytohistology correlation was found in 92 cases. Correct typing was done in 53.33% cases. No correlation was found in 14.81% cases. Material was unsatisfactory in 18.51% cases. The diagnostic accuracy and positive predictive values were 85.71% and 78.26%, respectively.
Although there are some limitations, most lesions of the anterior mediastinum can be diagnosed on FNAC.
本研究的主要目的是评估计算机断层扫描（CT）引导下前纵隔肿块细针穿刺抽吸细胞学检查（FNAC）作为一种诊断方法的效果。
在全部135例病例中，通过CT引导下FNAC技术获取材料，随后用巴氏染色法和迈-格-姬三色染色法进行染色。组织学材料通过针吸活检、楔形活检和切除标本获取。在部分病例中使用免疫组织化学染色来确诊。
135例病例中，92例存在细胞组织学相关性。53.33%的病例做出了正确分型。14.81%的病例未发现相关性。18.51%的病例材料不充分。诊断准确率和阳性预测值分别为85.71%和78.26%。
尽管存在一些局限性，但前纵隔的大多数病变可通过FNAC做出诊断。
