Zhu Lei-Lei, Meng Hong, Jiang Jian
Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 Jan;28(1):20-3.
To explore the method for TCM syndrome typing of chronic hepatitis B (CHB).
Clinical questionnaire of epidemiological investigation was established, by which the relative information from 871 patients with CHB was collected on the spot to conduct multi-analysis, including factor analysis, cluster analysis, correspondence analysis, etc. Then the population basic TCM syndrome types and the individual TCM syndrome type of patients were obtained adopting the new combination of factor analysis and variable cluster, and the corresponding relation between TCM syndrome type and the figures of tongue and pulse was analyzed as well.
Analysis on distribution of TCM syndrome type in patients showed that single syndrome type presented in 380 cases (43.6%), including Gan-Shen yin deficiency type in 126 (14.5%), Gan-Dan dampness-heat type in 126 (14.5%), Gan-depression and Pi-deficiency type in 128 (14.7%); compound syndrome type presented in 301 (34.6%); the other 190 patients (14.5%) without any symptom was regarded as no syndrome type. Multiple correspondence analysis showed that Gan-Shen yin deficiency type is related to red tongue, thin yellowish fur, and taut pulse; Gan-Dan dampness-heat type is related to yellowish greasy fur and slippery pulse; Gan-depression with Pi-deficiency type is related to thin whitish fur and taut thready pulse.
The above-mentioned typing of TCM syndrome well coincided with the clinical practice, and the correspondence between single syndrome type and the manifestation of tongue and pulse is obvious.
探索慢性乙型肝炎(CHB)的中医证型分类方法。
建立临床流行病学调查问卷,现场收集871例CHB患者的相关信息进行多分析,包括因子分析、聚类分析、对应分析等。然后采用因子分析与变量聚类的新组合方法得出人群基本中医证型和患者个体中医证型,并分析中医证型与舌脉表现的对应关系。
患者中医证型分布分析显示,单证型380例(43.6%),其中肝肾阴虚型126例(14.5%),肝胆湿热型126例(14.5%),肝郁脾虚型128例(14.7%);复合证型301例(34.6%);其余190例(14.5%)无症状者视为无证型。多重对应分析显示,肝肾阴虚型与舌红、苔薄黄、脉弦有关;肝胆湿热型与苔黄腻、脉滑有关;肝郁脾虚型与苔薄白、脉弦细有关。
上述中医证型分类与临床实际情况吻合较好,单证型与舌脉表现的对应关系明显。