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水平基因转移在某些食源性病原体进化中的作用。

The role of horizontal gene transfer in the evolution of selected foodborne bacterial pathogens.

作者信息

Kelly B G, Vespermann A, Bolton D J

机构信息

School of Food Science and Environmental Health, Dublin Institute of Technology, Cathal Brugha Street, Dublin 1, Ireland.

出版信息

Food Chem Toxicol. 2009 May;47(5):951-68. doi: 10.1016/j.fct.2008.02.006. Epub 2008 Feb 14.

Abstract

Bacteria use various ways to transfer genetic information. These methods include: conjugation, which requires cell to cell contact between cells, transduction, which is bacteriophage-facilitated transfer of genetic information, and transformation, which is the uptake of free DNA from the environment. Usually the genes to be transferred lie on mobile genetic elements, pieces of DNA that encode proteins important to facilitate movement of DNA within or between genomes. This review highlights the transfer methods and the role of the assorted mobile genetic elements in the evolution of four foodborne bacterial pathogens: Escherichia coli O157:H7, Salmonella, Staphylococcus aureus and Listeria monocytogenes.

摘要

细菌利用多种方式传递遗传信息。这些方法包括:接合,这需要细胞间的细胞接触;转导,即噬菌体介导的遗传信息传递;以及转化,即从环境中摄取游离DNA。通常,待转移的基因位于可移动遗传元件上,这些DNA片段编码有助于DNA在基因组内或基因组间移动的重要蛋白质。本综述重点介绍了四种食源性病原体(大肠杆菌O157:H7、沙门氏菌、金黄色葡萄球菌和单核细胞增生李斯特菌)的遗传信息传递方法以及各种可移动遗传元件在其进化中的作用。

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