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胶体囊肿的纯内镜切除术。

Purely endoscopic resection of colloid cysts.

作者信息

Greenlee Jeremy D W, Teo Charles, Ghahreman Ali, Kwok Bernard

机构信息

Department of Neurosurgery, University of Iowa, 200 West Hawkins Drive, Iowa City, IA 52242, USA.

出版信息

Neurosurgery. 2008 Mar;62(3 Suppl 1):51-5; discussion 55-6. doi: 10.1227/01.neu.0000317373.00018.6f.

Abstract

OBJECTIVE

To further assess the safety and long-term efficacy of endoscopic resection of colloid cysts of the third ventricle.

METHODS

A retrospective review of a series of 35 consecutive patients (18 male, 17 female) with colloid cysts treated by endoscopic surgery was undertaken.

RESULTS

The mean patient age was 32.4 years (range, 11-54 yr). Headache was the most common presenting symptom (22 patients). The average tumor size was 18 mm (range, 3-50 mm). The endoscopic technique could not be completed in six patients, necessitating conversion to an open craniotomy and a transcortical approach to the colloid cyst. All patients had histologically confirmed colloid cysts of the third ventricle, and complete resection of the lesion was confirmed macroscopically and radiologically in all patients. There were no deaths. Two patients developed aseptic meningitis without any permanent sequelae. One patient developed unilateral hydrocephalus attributable to obstruction of the foramen of Monro, which was treated with endoscopic septum pellucidotomy. The median follow-up period was 88 months (range, 10-132 mo). There was one asymptomatic radiological recurrence. No seizures occurred after surgery.

CONCLUSION

The results of this study support the role of endoscopic resection in the treatment of patients with colloid cysts as a safe and effective modality. In some cases, conversion to an open procedure may be required. Additional follow-up will be required to continue to address the duration of lesion-free survival.

摘要

目的

进一步评估经内镜切除第三脑室胶样囊肿的安全性和长期疗效。

方法

对连续35例接受内镜手术治疗的胶样囊肿患者(18例男性,17例女性)进行回顾性分析。

结果

患者平均年龄为32.4岁(范围11 - 54岁)。头痛是最常见的首发症状(22例患者)。肿瘤平均大小为18 mm(范围3 - 50 mm)。6例患者无法完成内镜操作,需要转为开颅手术并采用经皮质入路处理胶样囊肿。所有患者经组织学证实为第三脑室胶样囊肿,所有患者均在宏观和影像学上证实病变完全切除。无死亡病例。2例患者发生无菌性脑膜炎且无任何永久性后遗症。1例患者因Monro孔阻塞出现单侧脑积水,经内镜透明隔造瘘术治疗。中位随访期为88个月(范围10 - 132个月)。有1例无症状影像学复发。术后无癫痫发作。

结论

本研究结果支持经内镜切除在治疗胶样囊肿患者中作为一种安全有效的方式所起的作用。在某些情况下,可能需要转为开放手术。需要进一步随访以继续探讨无瘤生存期的时长。

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