Prasad R N, Virk K J, Ganguly N K, Mahajan R C
Malaria Research Centre, Shahjahanpur.
J Commun Dis. 1991 Dec;23(4):240-4.
Humoral immune response of normal rhesus monkeys was studied after giving a standard dose of primaquine. The drug did not effect the level of complement (C3) and its haemolytic activity. Levels of Immunoglobulin i.e. IgG, IgM & IgA and number of immunoglobulin secreting cells also remained unaffected. Results of this study suggested that primaquine did not suppress the immune status of the host and could be given safely to the malaria patients.
在给正常恒河猴注射标准剂量的伯氨喹后，对其体液免疫反应进行了研究。该药物对补体（C3）水平及其溶血活性没有影响。免疫球蛋白即IgG、IgM和IgA的水平以及免疫球蛋白分泌细胞的数量也未受影响。这项研究的结果表明，伯氨喹不会抑制宿主的免疫状态，可以安全地给予疟疾患者。
