用于评估潜在药物治疗剂治疗酒精中毒以及研究大鼠觅酒行为神经药理学基础的临床前模型。
Preclinical models to evaluate potential pharmacotherapeutic agents in treating alcoholism and studying the neuropharmacological bases of ethanol-seeking behaviors in rats.
作者信息
June Harry L
机构信息
Indiana University-Purdue University, Indianapolis, Indiana, USA.
出版信息
Curr Protoc Neurosci. 2002 Aug;Chapter 9:Unit 9.12. doi: 10.1002/0471142301.ns0912s19.
PMID:18428571
Abstract
The unit outlines four basic protocols designed to systematically evaluate the capacity of potential pharmacotherapeutic agents to effectively treat alcohol addiction and dependence in rats. Also included are procedures designed to study the neural mechanisms regulating alcohol-seeking behaviors.
摘要
该单元概述了四种基本方案，旨在系统评估潜在药物治疗剂有效治疗大鼠酒精成瘾和依赖的能力。其中还包括旨在研究调节觅酒行为的神经机制的程序。
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