用于蛋白质结构的FAMS和FAMSBASE。
FAMS and FAMSBASE for protein structure.
作者信息
Umeyama Hideaki, Iwadate Mitsuo
机构信息
Kitasato University, Tokyo, Japan.
出版信息
Curr Protoc Bioinformatics. 2004 Feb;Chapter 5:Unit5.2. doi: 10.1002/0471250953.bi0502s04.
The computer program FAMS (Full Automatic Modeling System) performs homology modeling of protein structures by means of an algorithm consisting of database searches and simulated annealing. FAMS produces a model in which the torsion angles of the backbone and sidechains are highly accurate. The operations of the FAMS algorithm are fully automated, and, therefore, special knowledge, techniques or experience are not required in order to obtain a biologically worthwhile protein structure.
计算机程序FAMS（全自动建模系统）通过一种由数据库搜索和模拟退火组成的算法来进行蛋白质结构的同源建模。FAMS生成的模型中，主链和侧链的扭转角高度精确。FAMS算法的操作完全自动化，因此，无需特殊知识、技术或经验就能获得具有生物学价值的蛋白质结构。
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