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外科治疗感染性心内膜炎病例的回顾性分析。

Retrospective analysis of surgically treated infective endocarditis cases.

作者信息

Burma Oktay, Atik Cem, Celkan M Adnan, Ustünsoy Haşim, Kazaz Hakki

机构信息

Department of Cardiovascular Surgery, School of Medicine, Gaziantep University, Gaziantep, Turkey.

出版信息

Heart Surg Forum. 2008;11(2):E90-3. doi: 10.1532/HSF98.20071179.

Abstract

BACKGROUND

Prosthetic valve endocarditis (PVE) and native valve endocarditis (NVE) both cause high rates of morbidity and mortality and are significant health problems in our community. Optimal timing of the surgical intervention depends on the hemodynamic stability of the patient. In the present study, we retrospectively evaluated the clinical status, bacteriology, morbidity, and mortality parameters of infective endocarditis cases that were treated surgically.

METHODS

Thirty patients (20 male and 10 female) who underwent cardiac valve surgery between April 2001 and December 2006 were included in the study. The mean (SD) age of the patients was 36.5 +/- 5.42 years. Thirty-five surgical operations were conducted on 30 patients. We evaluated the patient demographic, etiologic, and surgical data retrospectively with respect to mortality and morbidity.

RESULTS

The mean time to develop PVE was 13 months. We recorded a mortality rate of 16.6% (2 deaths in NVE operations and 3 deaths in PVE operations). Repeat surgeries were performed in 2 aortic valve cases and 3 mitral valve cases in which paravalvular leakage was noticed in the prosthetic valves.

CONCLUSION

Despite significant medical and surgical advances, both NVE and PVE still continue to be causes of high mortality and morbidity rates in cardiac surgery.

摘要

背景

人工瓣膜心内膜炎(PVE)和自体瓣膜心内膜炎(NVE)均导致高发病率和死亡率,是我们社区中的重大健康问题。手术干预的最佳时机取决于患者的血流动力学稳定性。在本研究中,我们回顾性评估了接受手术治疗的感染性心内膜炎病例的临床状况、细菌学、发病率和死亡率参数。

方法

本研究纳入了2001年4月至2006年12月期间接受心脏瓣膜手术的30例患者(20例男性和10例女性)。患者的平均(标准差)年龄为36.5±5.42岁。对30例患者进行了35次手术。我们回顾性评估了患者的人口统计学、病因学和手术数据的死亡率和发病率。

结果

发生PVE的平均时间为13个月。我们记录的死亡率为16.6%(NVE手术中有2例死亡,PVE手术中有3例死亡)。在2例主动脉瓣病例和3例二尖瓣病例中进行了再次手术,这些病例的人工瓣膜出现了瓣周漏。

结论

尽管在医学和外科方面取得了重大进展,但NVE和PVE仍然是心脏手术中高死亡率和发病率的原因。

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