Chaib E, Alves V A, Chaib S A
Departamento de Gastroenterologia, Hospital das Clínicas da Faculdade de Medicina, Universidade de São Paulo.
Arq Gastroenterol. 1991 Jul-Sep;28(3):103-6.
The authors reported a case of giant solitary pancreatic gastrinoma. A 29-year-old woman complaining of upper abdominal pain and loss of weight of 6 months duration. Four months later she noticed moving abdominal tumor. At the surgery a tumor was identified on pancreatic body measuring 20 centimeters of dimension and it was completely removed. A partial pancreatectomy with pancreatic tail preservation was performed in addition to this the Wirsung duct was joined on pancreatic head. No abdominal metastasis was found. The gastrointestinal transit was re-established by end-to-side Roux-en-Y jejunum-pancreatic anastomosis. The final diagnosis was confirmed by immunohistochemical test (immunoperoxidase). The follow-up was made until 40th postoperative month and after surgery the plasma level of gastrin was 120 pg/ml but at present day is normal. The authors concluded that it was a benign giant solitary pancreatic gastrinoma.
作者报告了一例巨大孤立性胰腺胃泌素瘤病例。一名29岁女性，主诉上腹部疼痛及体重减轻6个月。4个月后，她注意到腹部有可移动的肿块。手术中在胰体部发现一个大小为20厘米的肿瘤，并将其完整切除。除了保留胰尾进行部分胰腺切除外，还将主胰管与胰头部相连。未发现腹部转移。通过端侧Roux-en-Y空肠-胰腺吻合术重建了胃肠道通路。最终诊断通过免疫组织化学检测（免疫过氧化物酶法）得以证实。随访至术后第40个月，术后血浆胃泌素水平为120 pg/ml，但目前已恢复正常。作者得出结论，这是一例良性巨大孤立性胰腺胃泌素瘤。
