Miyamura T
Jpn J Med Sci Biol. 1976 Apr;29(2):53-65. doi: 10.7883/yoken1952.29.53.
The surface of the SV40-infected African green monkey kidney (AGMK) cells was studied morphologically by scanning electron microscopy. In 24 hr post infection (p.i.), the cell surface was covered with slightly elongated microvilli. The microvilli increased in number. In 96 hr.p.i. most of the cells showed SV40-specific cytopathic effects (CPE). Nuclear swellings and the elongation of microvilli were eminent. Microvilli were observed projecting with high densities especially on the nuclear portions of the cell surfaces. Features suggesting cytoplasmic vacuolization were also observed in some cells. Spherical particles viewed in some of the cells at the late stage of infection were considered SV40 virions. Their origin was also discussed.
通过扫描电子显微镜对感染SV40的非洲绿猴肾（AGMK）细胞表面进行了形态学研究。感染后24小时（p.i.），细胞表面覆盖着略微伸长的微绒毛。微绒毛数量增加。感染后96小时，大多数细胞显示出SV40特异性细胞病变效应（CPE）。核肿胀和微绒毛伸长明显。尤其在细胞表面的核部分观察到微绒毛高密度突出。在一些细胞中也观察到提示细胞质空泡化的特征。在感染后期的一些细胞中观察到的球形颗粒被认为是SV40病毒粒子。还讨论了它们的起源。
