Donovan John, Brown Patricia
Wyeth Research, Collegeville, Pennsylvania.
National Institutes of Health, Bethesda, Maryland.
Curr Protoc Immunol. 2006 Jul;Chapter 1:1.3.1-1.3.6. doi: 10.1002/0471142735.im0103s73.
For the safety of the handler and the animal, proper methods for handling and restraining laboratory animals should be followed. Improper handling can result in increased stress and injury to the animal. In addition, the handler risks injury from bite wounds or scratches inflicted when the animal becomes fearful or anxious. By using sure, direct movements with a determined attitude, the animal can be easily handled and restrained. Animals can be restrained either manually or in a plastic restrainer. The protocols in this unit describe handling and manual restraint of mice, rats, hamsters, and rabbits. Alternate protocols describe restraint using the plastic restrainer.
为了操作人员和动物的安全,应遵循处理和约束实验动物的正确方法。不当的处理会导致动物压力增加和受伤。此外,当动物变得恐惧或焦虑时,操作人员有被咬伤或抓伤的风险。通过以坚定的态度进行平稳、直接的动作,可以轻松地处理和约束动物。动物可以手动约束或放置在塑料约束器中。本单元中的方案描述了对小鼠、大鼠、仓鼠和兔子的处理及手动约束方法。其他方案则描述了使用塑料约束器进行约束的方法。