Dalmora S L, Assaf G S, Dalmora M E, Vaucher L C, Vaccari S F
Departamento de Farmćia Industrial, Universidade Federal de Santa Maria-RS.
Rev Hosp Clin Fac Med Sao Paulo. 1991 Mar-Apr;46(2):59-62.
Heparin samples from four manufacturers and the First Argentinian Standard Heparin obtained from porcine mucosa were assayed by the Reinert and Winterstein method, modified as suggested by USP and Brazilian Pharmacopeias. Other methods described in the literature and their importance for the evaluation of anticoagulant activity of unfractionated heparins with low molecular weight are discussed.
采用经美国药典和巴西药典建议修改的赖纳特和温特施泰因方法,对来自四个制造商的肝素样品以及从猪黏膜中提取的阿根廷第一标准肝素进行了检测。还讨论了文献中描述的其他方法及其对评估低分子量普通肝素抗凝活性的重要性。