Kandinov Boris, Giladi Nir, Korczyn Amos D
Department of Physiology and Pharmacology, Tel Aviv University, Tel Aviv, Israel.
Parkinsonism Relat Disord. 2009 Jan;15(1):41-6. doi: 10.1016/j.parkreldis.2008.02.011. Epub 2008 Apr 23.
Cigarette smoking, coffee and tea drinking may protect against Parkinson's disease (PD). These factors were assessed, retrospectively, to measure their effect on the age of PD onset. The study population consisted of 278 consecutive PD patients. Smoking > or =10 pack-years delayed age of PD onset by 3.2 years (p<0.05). Consumption of tea more than 3 cups per day delayed age of motor symptoms onset by 7.7 years (p<0.01). Coffee consumption exceeding 3 cups per day advanced the age of PD onset by 4.8 years (p=0.03). Thus, tea consumption and smoking can delay the age of PD onset, while coffee drinking may have the opposite effect.
吸烟、喝咖啡和喝茶可能预防帕金森病(PD)。对这些因素进行了回顾性评估,以衡量它们对帕金森病发病年龄的影响。研究人群包括278例连续的帕金森病患者。吸烟≥10包年使帕金森病发病年龄延迟3.2年(p<0.05)。每天饮用超过3杯茶使运动症状发病年龄延迟7.7年(p<0.01)。每天饮用超过3杯咖啡使帕金森病发病年龄提前4.8年(p=0.03)。因此,喝茶和吸烟可延迟帕金森病发病年龄,而喝咖啡可能有相反的作用。