Raschka Sonja, Raschka Christoph
Chirurgische Abteilung, Helios St. Elisabeth Klinik, Hünfeld.
Anthropol Anz. 2008 Mar;66(1):67-72.
In the last decades a lot of significant correlations between clinical and anthropometric parameters were found, e.g. the relationships between somatotypical and endocrine parameters or between body dimensions and echocardiographic heart size. During operation, surgeons often find a wide range of appendix size of patients with varying body dimensions. A goal of this work is the detection of the relationships between anthropometric characteristics (height, weight, body mass index (= BMI)), inflammation parameters (histological inflammation degree, leukocyte count and C-reactive protein (= CRP)) and the appendix length with n=167 consecutive patients (time period 1.1.2004 - 31.12.2006; range of age 7-95 years, median age 20 years; average age of men 27.7, women 26.6 years), which had to be operated because of acute appendicitis. Appendectomy was laparoscopic in 95 % of the patients and open in 5 %. The appendix length of the male patients was high-significantly longer with a mean of 7.5 cm (SD = 2.1) than those of the female patients with 6.3 cm (SD = 1.6). The following mean anthropometric values were registered: height 169.8 (SD = 15.6) cm for the males and 165.2 (SD = 9.6) cm for the females, weight 70.4 (SD = 23.4) kg for the males and 61.9 (SD = 16.1) kg for the females, BMI 24.1 (SD = 5.4) kg/m2 for the males and 22.9 (SD = 4.8) kg/m2 for the females. The mean leukocyte count was 12,700 (SD = 5500)/ml for the males and 11,600 (SD = 4900)/ml for the females, CRP was 4.3 (SD = 5.4) mg/l for the males and 4.5 (SD = 8.9) mg/l for the females. Concerning the histopathological diagnosis, n=76 patients (45.5 %) suffered from a submucous fibrosis bliteration, n 1 (12.6 ) from an acute purulent inflammation degree, n = 65 (38.9 ) from an ulcerative hlegmonous inflammation degree and n (3 ) from a perforation. While no significant Spearman's correlation coefficient between appendix length and CRP was found, the appendix length correlated highly significantly to the body weight (r = 0.25) and significantly to leukocyte count (r = 0.16), body height (r = 0.16), BMI (r = 0.17) and the histological inflammation degree (r = 0.18). Thus, the correlations found were lower than the relationships between anthropometric and endocrine or echocardiographic parameters described in literature.
在过去几十年间,人们发现了许多临床参数与人体测量学参数之间的显著相关性,例如体型与内分泌参数之间的关系,或者身体尺寸与超声心动图测量的心脏大小之间的关系。在手术过程中,外科医生经常会发现,不同体型患者的阑尾大小差异很大。本研究的目的是检测167例因急性阑尾炎而接受手术的连续患者(时间段为2004年1月1日至2006年12月31日;年龄范围为7至95岁,中位年龄为20岁;男性平均年龄为27.7岁,女性为26.6岁)的人体测量学特征(身高、体重、体重指数(=BMI))、炎症参数(组织学炎症程度、白细胞计数和C反应蛋白(=CRP))与阑尾长度之间的关系。95%的患者接受了腹腔镜阑尾切除术,5%的患者接受了开腹阑尾切除术。男性患者的阑尾长度明显更长,平均为7.5厘米(标准差=2.1),而女性患者的阑尾长度平均为6.3厘米(标准差=1.6)。记录的人体测量学平均值如下:男性身高为169.8(标准差=15.6)厘米,女性为165.2(标准差=9.6)厘米;男性体重为70.4(标准差=23.4)千克,女性为61.9(标准差=16.1)千克;男性BMI为24.1(标准差=5.4)千克/平方米,女性为22.9(标准差=4.8)千克/平方米。男性白细胞计数平均为12,700(标准差=5500)/毫升,女性为11,600(标准差=4900)/毫升;男性CRP为4.3(标准差=5.4)毫克/升,女性为4.5(标准差=8.9)毫克/升。关于组织病理学诊断,76例患者(45.5%)患有黏膜下纤维化闭塞,1例(1.2%)患有急性化脓性炎症,65例(38.9%)患有溃疡性蜂窝织炎,20例(12.0%)患有穿孔。虽然未发现阑尾长度与CRP之间存在显著的斯皮尔曼相关系数,但阑尾长度与体重(r = 0.25)、白细胞计数(r = 0.16)、身高(r = 0.16)、BMI(r = 0.17)和组织学炎症程度(r = 0.18)高度显著相关。因此,所发现的相关性低于文献中描述的人体测量学与内分泌或超声心动图参数之间的关系。