Yang Jian, Zhu Dunwan, Leng Xigang, Zhang Hailing, Song Liping, Yao Kangde
Research Institute of Polymeric Materials, Tianjin University, Tianjin 300072, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2008 Feb;25(1):215-9.
The biosafety of gene delivery vectors has received much more attention in recent years. In this article, the biosafety of non-viral gene delivery vectors was mainly discussed. Recent developments in researches on toxicity, nano-effect, blood compatibility and immune response of non-viral gene delivery vectors were reviewed.
近年来,基因递送载体的生物安全性受到了更多关注。本文主要讨论了非病毒基因递送载体的生物安全性。综述了非病毒基因递送载体在毒性、纳米效应、血液相容性和免疫反应等方面的研究进展。