Stutte H J, Arnaudow M
Laryngol Rhinol Otol (Stuttg). 1976 Jul;55(7):575-80.
Indirect lymphography is shown to be a technically uncomplicated and easy to use method of displaying the lymph nodes and -vessels of the face and neck regions. "Lipiodol-Ultra-Fluid" an oily contrast medium which has used in experiments with minipigs can be radiologically and histologically demonstrated in nodes for months. The histological findings in the course of a year are, at the beginning a phase of non-specific reaction followed by a phase of granulomatous reaction between two weeks and six weeks and finally a third phase where in the medium is stored virtually without histological reaction and is only reduced very slowly. Irreversible destruction of lymph-node structure as not infrequently follows the direct method - due to high-pressure application of the fluid was not evident. It may be assumed that disturbance of lymph node function or changes in lymph flow do not follow the application of the indirect method of lymphography.